dc.contributor.advisor | Rodríguez Lichtenheldt, José Edwin Adalberto | es_PE |
dc.contributor.author | Cama Arias , Giancarlo Cama | es_PE |
dc.contributor.author | Peralta Rodriguez, Reyna Kelly | es_PE |
dc.date.accessioned | 2024-04-29T15:21:47Z | |
dc.date.available | 2024-04-29T15:21:47Z | |
dc.date.issued | 2024-04-12 | |
dc.identifier.uri | https://hdl.handle.net/20.500.12970/2084 | |
dc.description.abstract | Objetivo: evaluar la actividad antibacteriana el extracto hidroalcohólico de hojas de Muña (Minthostachys mollis) frente a la cepa de E. coli ATCC 25922.
Método: se preparó un extracto hidroalcohólico de Muña, se realizaron las pruebas de tamizaje fitoquímico y evaluación de la actividad antibacteriana empleando diversos antibióticos como control positivo, aplicando el método del Método Kirby Bauer. Para establecer la similitud y diferencia de los grupos se procedió a realizar el test de Tukey
Resultado: el extracto hidroalcohólico con las hojas de Muña presentó actividad antibacteriana frente E. coli ATCC 25922, revelando halo de inhibición promedio de 16.68 mm al 25%, 17.92 mm al 50% y 18.81 mm al 75%, valores que al ser comparados con los antibióticos mediante el test de Tukey al 95% de confianza mostro que no hay diferencia significativa con la amikacina. El tamizaje fitoquímico identificó notable presencia de Fenoles; moderada presencia de taninos, flavonoides y poca presencia de alcaloides.
Conclusión: el extracto hidroalcohólico con las hojas de Muña (Minthostachys mollis) presenta actividad antibacteriana frente a la cepa E. coli ATCC 25922 en sus diversas concentraciones, siendo el metabolito secundario mayoritario los Fenoles. | es_PE |
dc.description.abstract | Objective: to evaluate the antibacterial activity of the hydroalcoholic extract of Muña leaves (Minthostachys mollis) against the E. coli strain ATCC 25922.
Method: a hydroalcoholic extract of Muña was prepared, phytochemical screening tests and evaluation of antibacterial activity were carried out using various antibiotics as a positive control, applying the Kirby Bauer Method. To establish the similarity and difference of the groups, the Tukey test was performed.
Result: the hydroalcoholic extract with Muña leaves presented antibacterial activity against E. coli ATCC 25922, revealing an average inhibition zone of 16.68 mm at 25%, 17.92 mm at 50% and 18.81 mm at 75%, values that when compared with antibiotics using the Tukey test at 95% confidence showed that there is no significant difference with amikacin. Phytochemical screening identified a notable presence of Phenols; moderate presence of tannins, flavonoids and little presence of alkaloids.
Conclusion: the hydroalcoholic extract with Muña leaves (Minthostachys mollis) presents antibacterial activity against the E. coli ATCC 25922 strain in its various concentrations, the majority secondary metabolite being Phenols | es_PE |
dc.format | application/pdf | es_PE |
dc.language.iso | spa | es_PE |
dc.publisher | Universidad María Auxiliadora | es_PE |
dc.rights | info:eu-repo/semantics/openAccess | es_PE |
dc.rights.uri | https://creativecommons.org/licenses/by/4.0/ | es_PE |
dc.subject | Actividad antibacteriana | es_PE |
dc.subject | Minthostachys Mollis | es_PE |
dc.subject | Extracto hidroalcohólico | es_PE |
dc.subject | Escherichia coli | es_PE |
dc.subject | Antibacterial activity | es_PE |
dc.subject | Hydroalcoholic Extract | es_PE |
dc.title | Actividad antibacteriana del extracto hidroalcohólico de hojas de Muña (Minthostachys Mollis) sobre la cepa de Escherichia Coli ATCC 25922 | es_PE |
dc.title.alternative | Antibacterial activity of the extract hydroalcoholic from Muña leaves (Minthostachys Mollis) on the strain of Escherichia Coli ATCC 25922 | es_PE |
dc.type | info:eu-repo/semantics/bachelorThesis | es_PE |
dc.publisher.country | PE | es_PE |
dc.subject.ocde | https://purl.org/pe-repo/ocde/ford#3.01.05 | es_PE |
dc.type.version | info:eu-repo/semantics/acceptedVersion | es_PE |
thesis.degree.discipline | Farmacia y Bioquímica | es_PE |
thesis.degree.grantor | Universidad María Auxiliadora. Facultad de Ciencias de la Salud. | es_PE |
thesis.degree.name | Químico Farmacéutico | es_PE |
renati.advisor.dni | 10734121 | |
renati.advisor.orcid | https://orcid.org/0000-0003-1876-6496 | es_PE |
renati.author.dni | 46932999 | |
renati.author.dni | 72550330 | |
renati.discipline | 917046 | es_PE |
renati.juror | La Serna La Rosa, Pablo Antonio | es_PE |
renati.juror | Herrera Rivas, Mirtha Rosabell | es_PE |
renati.juror | Dionicio Escalante, Elisa Roxana | es_PE |
renati.level | https://purl.org/pe-repo/renati/level#tituloProfesional | es_PE |
renati.type | https://purl.org/pe-repo/renati/type#tesis | es_PE |