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dc.contributor.advisorRodríguez Lichtenheldt, José Edwin Adalbertoes_PE
dc.contributor.authorCama Arias , Giancarlo Camaes_PE
dc.contributor.authorPeralta Rodriguez, Reyna Kellyes_PE
dc.date.accessioned2024-04-29T15:21:47Z
dc.date.available2024-04-29T15:21:47Z
dc.date.issued2024-04-12
dc.identifier.urihttps://hdl.handle.net/20.500.12970/2084
dc.description.abstractObjetivo: evaluar la actividad antibacteriana el extracto hidroalcohólico de hojas de Muña (Minthostachys mollis) frente a la cepa de E. coli ATCC 25922. Método: se preparó un extracto hidroalcohólico de Muña, se realizaron las pruebas de tamizaje fitoquímico y evaluación de la actividad antibacteriana empleando diversos antibióticos como control positivo, aplicando el método del Método Kirby Bauer. Para establecer la similitud y diferencia de los grupos se procedió a realizar el test de Tukey Resultado: el extracto hidroalcohólico con las hojas de Muña presentó actividad antibacteriana frente E. coli ATCC 25922, revelando halo de inhibición promedio de 16.68 mm al 25%, 17.92 mm al 50% y 18.81 mm al 75%, valores que al ser comparados con los antibióticos mediante el test de Tukey al 95% de confianza mostro que no hay diferencia significativa con la amikacina. El tamizaje fitoquímico identificó notable presencia de Fenoles; moderada presencia de taninos, flavonoides y poca presencia de alcaloides. Conclusión: el extracto hidroalcohólico con las hojas de Muña (Minthostachys mollis) presenta actividad antibacteriana frente a la cepa E. coli ATCC 25922 en sus diversas concentraciones, siendo el metabolito secundario mayoritario los Fenoles.es_PE
dc.description.abstractObjective: to evaluate the antibacterial activity of the hydroalcoholic extract of Muña leaves (Minthostachys mollis) against the E. coli strain ATCC 25922. Method: a hydroalcoholic extract of Muña was prepared, phytochemical screening tests and evaluation of antibacterial activity were carried out using various antibiotics as a positive control, applying the Kirby Bauer Method. To establish the similarity and difference of the groups, the Tukey test was performed. Result: the hydroalcoholic extract with Muña leaves presented antibacterial activity against E. coli ATCC 25922, revealing an average inhibition zone of 16.68 mm at 25%, 17.92 mm at 50% and 18.81 mm at 75%, values that when compared with antibiotics using the Tukey test at 95% confidence showed that there is no significant difference with amikacin. Phytochemical screening identified a notable presence of Phenols; moderate presence of tannins, flavonoids and little presence of alkaloids. Conclusion: the hydroalcoholic extract with Muña leaves (Minthostachys mollis) presents antibacterial activity against the E. coli ATCC 25922 strain in its various concentrations, the majority secondary metabolite being Phenolses_PE
dc.formatapplication/pdfes_PE
dc.language.isospaes_PE
dc.publisherUniversidad María Auxiliadoraes_PE
dc.rightsinfo:eu-repo/semantics/openAccesses_PE
dc.rights.urihttps://creativecommons.org/licenses/by/4.0/es_PE
dc.subjectActividad antibacterianaes_PE
dc.subjectMinthostachys Mollises_PE
dc.subjectExtracto hidroalcohólicoes_PE
dc.subjectEscherichia colies_PE
dc.subjectAntibacterial activityes_PE
dc.subjectHydroalcoholic Extractes_PE
dc.titleActividad antibacteriana del extracto hidroalcohólico de hojas de Muña (Minthostachys Mollis) sobre la cepa de Escherichia Coli ATCC 25922es_PE
dc.title.alternativeAntibacterial activity of the extract hydroalcoholic from Muña leaves (Minthostachys Mollis) on the strain of Escherichia Coli ATCC 25922es_PE
dc.typeinfo:eu-repo/semantics/bachelorThesises_PE
dc.publisher.countryPEes_PE
dc.subject.ocdehttps://purl.org/pe-repo/ocde/ford#3.01.05es_PE
dc.type.versioninfo:eu-repo/semantics/acceptedVersiones_PE
thesis.degree.disciplineFarmacia y Bioquímicaes_PE
thesis.degree.grantorUniversidad María Auxiliadora. Facultad de Ciencias de la Salud.es_PE
thesis.degree.nameQuímico Farmacéuticoes_PE
renati.advisor.dni10734121
renati.advisor.orcidhttps://orcid.org/0000-0003-1876-6496es_PE
renati.author.dni46932999
renati.author.dni72550330
renati.discipline917046es_PE
renati.jurorLa Serna La Rosa, Pablo Antonioes_PE
renati.jurorHerrera Rivas, Mirtha Rosabelles_PE
renati.jurorDionicio Escalante, Elisa Roxanaes_PE
renati.levelhttps://purl.org/pe-repo/renati/level#tituloProfesionales_PE
renati.typehttps://purl.org/pe-repo/renati/type#tesises_PE


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